AIRE Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all AIRE 蛋白
- AIRE (Autoimmune Regulator (AIRE))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This AIRE protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human AIRE / APECED (transcript variant AIRE-1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Discover our top product AIRE 蛋白
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Autoimmune Regulator (AIRE) (AA 1-545) protein (Strep Tag)
Crystallography grade AIRE 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Autoimmune Regulator (AIRE) (AA 1-552) protein (Strep Tag)Crystallography grade AIRE 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- AIRE (Autoimmune Regulator (AIRE))
- 别名
- Aire,apeced (AIRE 产品)
- 别名
- AIRE1 Protein, APECED Protein, APS1 Protein, APSI Protein, PGA1 Protein, autoimmune regulator Protein, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) Protein, AaeL_AAEL013794 Protein, CpipJ_CPIJ001208 Protein, CpipJ_CPIJ001209 Protein, AIRE Protein, Aire Protein
- 背景
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- 分子量
- 57.5 kDa
- NCBI登录号
- NP_000374
- 途径
- Chromatin Binding
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