AIRE 产品
(Autoimmune Regulator (AIRE))
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This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012].
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Featured AIRE Categories
AIRE 抗体
High quality antibodies with extensive validation data.
AIRE ELISA试剂盒
Reliable ELISA kits for a wide range of species.
AIRE 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AIRE 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC, FACS
Validations
- (8)
Cat. No.
ABIN184780
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN3022515
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN2779777
Quantity
100 μL
Datasheet
Datasheet
Recommended AIRE ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965095
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954016
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954017
Quantity
96 tests
Datasheet
Datasheet
Recommended AIRE 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3088935
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3137558
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396196
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AIRE Products
: "Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats." in: Fibrogenesis & tissue repair, Vol. 8, pp. 12, (2015) (PubMed).: "Transcriptional and histological analyses of the thymic developmental process in the fetal pig." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014) (PubMed).
: "Corticomedullary differentiation and maturational arrest in thymomas." in: Histopathology, Vol. 64, Issue 4, pp. 557-66, (2014) (PubMed).
: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." in: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).
: "The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism." in: The Journal of physiology, Vol. 589, Issue Pt 22, pp. 5349-59, (2011) (PubMed).
: "Role of mast cell activation in inducing microglial cells to release neurotrophin." in: Journal of neuroscience research, Vol. 88, Issue 6, pp. 1348-54, (2010) (PubMed).
: "SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury." in: The Journal of comparative neurology, Vol. 517, Issue 5, pp. 670-82, (2009) (PubMed).
: "Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1292-301, (2006) (PubMed).
: "AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix." in: Molecular immunology, Vol. 43, Issue 4, pp. 335-45, (2005) (PubMed).
: "The autoimmune regulator (AIRE) is a DNA-binding protein." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41357-64, (2001) (PubMed).
Synonyms and alternative names related to AIRE
autoimmune regulator (AaeL_AAEL013794), autoimmune regulator (CpipJ_CPIJ001208), autoimmune regulator (CpipJ_CPIJ001209), autoimmune regulator (AIRE), autoimmune regulator (Aire), autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) (Aire), AIRE1, APECED, APS1, APSI, PGA1Protein level used designations for AIRE
- autoimmune regulator
- autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein
- autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- APECED protein homolog
- autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog
- autoimmune regulator AIRE1a
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