AIRE 蛋白
(Autoimmune Regulator (AIRE))
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012].
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custom-made
AIRE
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
AIRE
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aliases for AIRE 蛋白
autoimmune regulator (AaeL_AAEL013794) 蛋白autoimmune regulator (CpipJ_CPIJ001208) 蛋白
autoimmune regulator (CpipJ_CPIJ001209) 蛋白
autoimmune regulator (AIRE) 蛋白
autoimmune regulator (Aire) 蛋白
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) (Aire) 蛋白
AIRE1 蛋白
APECED 蛋白
APS1 蛋白
APSI 蛋白
PGA1 蛋白
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