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AKAP8 产品

(A Kinase (PRKA) Anchor Protein 8 (AKAP8))

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This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011].

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Featured AKAP8 Categories

AKAP8 抗体

High quality antibodies with extensive validation data.

AKAP8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AKAP8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), IP
Validations
  • (7)
Cat. No. ABIN564456
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
Cat. No. ABIN6259857
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN523683
Quantity 50 μg
Datasheet Datasheet

Recommended AKAP8 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648125
Quantity 96 tests
Datasheet Datasheet

Recommended AKAP8 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344731
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344733
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3088456
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our AKAP8 Products

Li, Kao, Garcia, Shabanowitz, Hunt, Qin, Phelan, Lazar: "A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity." in: Genes & development, Vol. 20, Issue 18, pp. 2566-79, (2006) (PubMed).

Schillace, Andrews, Liberty, Davey, Carr: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).

Collas, Le Guellec, Taskén: "The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis." in: The Journal of cell biology, Vol. 147, Issue 6, pp. 1167-80, (2000) (PubMed).

Steen, Cubizolles, Le Guellec, Collas: "A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract." in: The Journal of cell biology, Vol. 149, Issue 3, pp. 531-6, (2000) (PubMed).

Steen, Martins, Taskén, Collas: "Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly." in: The Journal of cell biology, Vol. 150, Issue 6, pp. 1251-62, (2000) (PubMed).

Eide, Coghlan, Orstavik, Holsve, Solberg, Skâlhegg, Lamb, Langeberg, Fernandez, Scott, Jahnsen, Taskén: "Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95." in: Experimental cell research, Vol. 238, Issue 2, pp. 305-16, (1998) (PubMed).

Synonyms and alternative names related to AKAP8

A-kinase anchoring protein 8 (AKAP8), A-kinase anchoring protein 8 (akap8), A kinase (PRKA) anchor protein 8 (Akap8), A-kinase anchoring protein 8 (Akap8), 1200016A02Rik, AA673585, AKAP-8, AKAP-95, AKAP8, AKAP 95, AKAP95, Akap95, AU015639, MGC108502

Protein level used designations for AKAP8

  • A kinase (PRKA) anchor protein 8
  • A-kinase anchor protein 8
  • A-kinase anchor protein 8-like
  • a-kinase anchor protein 8-like
  • A-kinase anchor protein, 95kDa
  • A kinase anchor protein 8
  • A kinase anchor protein 95
  • A-kinase anchor protein 95 kDa
  • AKAP 95
  • AKAP-8
  • protein kinase A-anchoring protein 95
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