C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
CLEC4M
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- 抗原 See all C-Type Lectin Domain Family 4, Member M (CLEC4M) 蛋白
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- Myc-DYKDDDDK Tag
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CD299 / CLEC4M (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CLEC4M 蛋白
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C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag)
CLEC4M 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- 别名
- Cd299,clec4m (CLEC4M 产品)
- 别名
- CD209L Protein, CD299 Protein, DC-SIGN2 Protein, DC-SIGNR Protein, DCSIGNR Protein, HP10347 Protein, L-SIGN Protein, LSIGN Protein, CD209B Protein, C-type lectin domain family 4 member M Protein, CLEC4M Protein
- 背景
- This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835 often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].
- 分子量
- 45.2 kDa
- NCBI登录号
- NP_055072
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