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C-Type Lectin Domain Family 4, Member M 蛋白

(C-Type Lectin Domain Family 4, Member M (CLEC4M))
This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].
C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag) (ABIN1349664)

CLEC4M 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (rho-1D4 tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (rho-1D4 tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (rho-1D4 tag) (ABIN3118083)

Crystallography grade CLEC4M 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag) C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag) (ABIN3091840)

Crystallography grade CLEC4M 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

C-Type Lectin Domain Family 4, Member M 蛋白 by Grade

Find C-Type Lectin Domain Family 4, Member M 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

C-Type Lectin Domain Family 4, Member M 蛋白 by Origin

Find C-Type Lectin Domain Family 4, Member M 蛋白 for a variety of species such as anti-Human C-Type Lectin Domain Family 4, Member M, anti-Chimpanzee C-Type Lectin Domain Family 4, Member M. The species listed below are among those available. Click on a link to go to the corresponding products.

C-Type Lectin Domain Family 4, Member M 蛋白 by Source

Here you will find C-Type Lectin Domain Family 4, Member M 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

C-Type Lectin Domain Family 4, Member M 蛋白 by 蛋白类型

Here you can find C-Type Lectin Domain Family 4, Member M 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

C-Type Lectin Domain Family 4, Member M 蛋白 by 应用范围

Find C-Type Lectin Domain Family 4, Member M 蛋白 validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular C-Type Lectin Domain Family 4, Member M 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349664
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3118083
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091840
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7504305
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7504304
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413766
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7194490
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2716811
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713616
Quantity 20 μg
Datasheet Datasheet
Reactivity Chimpanzee
Source Yeast
Validations
Cat. No. ABIN1636713
Quantity 1 mg
Datasheet Datasheet

Aliases for C-Type Lectin Domain Family 4, Member M 蛋白

C-type lectin domain family 4 member M (CLEC4M) 蛋白
CD209B 蛋白
CD209L 蛋白
CD299 蛋白
DC-SIGN2 蛋白
DC-SIGNR 蛋白
DCSIGNR 蛋白
HP10347 蛋白
L-SIGN 蛋白
LSIGN 蛋白
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