ERCC5 Protein (Myc-DYKDDDDK Tag)
ERCC5
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ERCC5 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human ERCC5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Discover our top product ERCC5 蛋白
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DNA Repair Protein Complementing XP-G Cells (ERCC5) protein
ERCC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- 别名
- Ercc5 (ERCC5 产品)
- 别名
- COFS3 Protein, ERCM2 Protein, UVDR Protein, XPG Protein, XPGC Protein, cofs3 Protein, ercm2 Protein, uvdr Protein, xpg Protein, xpgc Protein, Xpg Protein, ERCC excision repair 5, endonuclease Protein, excision repair cross-complementation group 5 L homeolog Protein, excision repair cross-complementing rodent repair deficiency, complementation group 5 Protein, ERCC5 Protein, ercc5.L Protein, Ercc5 Protein
- 背景
- This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.
- 分子量
- 133.1 kDa
- NCBI登录号
- NP_000114
- 途径
- DNA Damage Repair
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