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ERCC5 产品

(DNA Repair Protein Complementing XP-G Cells (ERCC5))

Categories

This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011].

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Featured ERCC5 Categories

ERCC5 抗体

High quality antibodies with extensive validation data.

ERCC5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ERCC5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ERCC5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7434239
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257134
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7300668
Quantity 100 μL
Datasheet Datasheet

Recommended ERCC5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955423
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648051
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1130135
Quantity 96 tests
Datasheet Datasheet

Recommended ERCC5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133879
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092497
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395086
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ERCC5 Products

Lemoine, Bayrambey, Roloff, Hutzler, Luch, Tralau: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).

Tillhon, Cazzalini, Nardo, Necchi, Sommatis, Stivala, Scovassi, Prosperi: "p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG." in: DNA repair, Vol. 11, Issue 10, pp. 844-52, (2012) (PubMed).

Wang, Han, Milum, Wani: "Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment." in: Mutation research, Vol. 708, Issue 1-2, pp. 59-68, (2011) (PubMed).

Synonyms and alternative names related to ERCC5

ERCC excision repair 5, endonuclease (ERCC5), excision repair cross-complementation group 5 L homeolog (ercc5.L), excision repair cross-complementing rodent repair deficiency, complementation group 5 (Ercc5), ERCC excision repair 5, endonuclease (Ercc5), COFS3, cofs3, ERCM2, ercm2, UVDR, uvdr, XPG, xpg, Xpg, XPGC, xpgc

Protein level used designations for ERCC5

  • DNA repair protein complementing XP-G cells
  • excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))
  • DNA excision repair protein ERCC-5
  • XPG-complementing protein
  • xeroderma pigmentosum, complementation group G
  • DNA repair protein complementing XP-G cells homolog
  • DNA-repair protein complementing XP-G cells homolog
  • XP-G related factor
  • xeroderma pigmentosum group G-complementing protein homolog
  • XPG
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