ERCC6L 产品
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
Categories
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
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Featured ERCC6L Categories
Recommended ERCC6L 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
- (3)
Cat. No.
ABIN565778
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN527206
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (6)
- (2)
Cat. No.
ABIN527207
Quantity
100 μg
Datasheet
Datasheet
Recommended ERCC6L ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228431
Quantity
96 tests
Datasheet
Datasheet
Recommended ERCC6L 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353041
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3092403
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136167
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ERCC6L Products
: "A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation." in: Journal of cell science, Vol. 129, Issue 16, pp. 3167-77, (2016) (PubMed).: "Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions." in: Nature communications, Vol. 6, pp. 10132, (2015) (PubMed).
: "PTEN stabilizes TOP2A and regulates the DNA decatenation." in: Scientific reports, Vol. 5, pp. 17873, (2015) (PubMed).
: "A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5605-15, (2014) (PubMed).
: "Bloom's syndrome and PICH helicases cooperate with topoisomerase II? in centromere disjunction before anaphase." in: PLoS ONE, Vol. 7, Issue 4, pp. e33905, (2012) (PubMed).
: "RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40618-28, (2012) (PubMed).
: "The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation." in: Nucleic acids research, Vol. 39, Issue 14, pp. 5935-44, (2011) (PubMed).
: "PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture." in: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1188-99, (2010) (PubMed).
: "Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 10, pp. 1480-9, (2008) (PubMed).
Synonyms and alternative names related to ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), excision repair cross-complementing rodent repair deficiency complementation group 6 like (Ercc6l), ERCC excision repair 6 like, spindle assembly checkpoint helicase (Ercc6l), DNA excision repair protein ERCC-6-like (LOC100373376), DNA excision repair protein ERCC-6-like (LOC100494766), DNA excision repair protein ERCC-6-like (LOC100552957), DNA excision repair protein ERCC-6-like (LOC100560751), DNA excision repair protein ERCC-6-like (LOC100563247), excision repair cross-complementation group 6-like (ercc6l), BC004701, D330021P09Rik, fc22h03, PICH, RAD26L, RGD1565734, si:ch211-278b8.3, wu:fc22h03Protein level used designations for ERCC6L
- ATP-dependent helicase ERCC6-like
- DNA excision repair protein ERCC-6-like
- Plk1-interacting checkpoint helicase
- SNF2/RAD54 family protein
- excision repair cross-complementing rodent repair deficiency complementation group 6 - like
- excision repair protein ERCC6-like
- tumor antigen BJ-HCC-15
- excision repair cross-complementing rodent repair deficiency complementation group 6-like
- excision repair cross-complementing rodent repair deficiency, complementation group 6-like
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