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ERCC8 产品

(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

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This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq, Jul 2008].

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Featured ERCC8 Categories

ERCC8 抗体

High quality antibodies with extensive validation data.

ERCC8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ERCC8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Horse, Human, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (10)
Cat. No. ABIN2777347
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN5577493
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, ICC
Validations
  • (4)
Cat. No. ABIN2857074
Quantity 100 μL
Datasheet Datasheet

Recommended ERCC8 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353045
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353043
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092404
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ERCC8 Products

Fleury, Carmona, Morin, Meunier, Masson, Tonin, Provencher, Mes-Masson: "Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines." in: Oncotarget, Vol. 8, Issue 25, pp. 40152-40168, (2018) (PubMed).

Synonyms and alternative names related to ERCC8

excision repair cross-complementation group 8 (ercc8), ERCC excision repair 8, CSA ubiquitin ligase complex subunit (ERCC8), ERCC excision repair 8, CSA ubiquitin ligase complex subunit (Ercc8), excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), 2410022P04Rik, 2810431L23Rik, 4631412O06Rik, B130065P18Rik, CKN1, Ckn1, CSA, Csa, UVSS2, zgc:103550

Protein level used designations for ERCC8

  • DNA excision repair protein ERCC-8
  • Cockayne syndrome 1 protein
  • Cockayne syndrome WD-repeat protein CSA
  • cockayne syndrome WD repeat protein CSA
  • Cockayne syndrome 1 (classical)
  • excision repaiross-complementing rodent repair deficiency, complementation group 8
  • Cockayne syndrome 1 homolog
  • cockayne syndrome WD repeat protein CSA homolog
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