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VLDLR Protein (His tag)

VLDLR 宿主: 人 宿主: HEK-293 Cells Recombinant >97 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN2567025
发货至: 中国
  • 抗原 See all VLDLR 蛋白
    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 3
    • 1
    资源
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This VLDLR protein is labelled with His tag.
    应用范围
    Western Blotting (WB), ELISA
    产品特性

    Measured by its binding ability in a functional ELISA. When Recombinant Human Apolipoprotein E3 is immobilized at 1 μg/mL (100 μL/well), the concentration of Recombinant Human VLDLR that produces 50 % of the optimal binding response is found to be approximately 0. 03 - 0. 15 μg/mL.

    纯度
    >97 % as determined by SDS-PAGE.
    Top Product
    Discover our top product VLDLR 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
    别名
    VLDLR (VLDLR 产品)
    别名
    CARMQ1 Protein, CHRMQ1 Protein, VLDLRCH Protein, AA408956 Protein, AI451093 Protein, AW047288 Protein, vldlr Protein, very low density lipoprotein receptor Protein, very low density lipoprotein receptor S homeolog Protein, VLDLR Protein, Vldlr Protein, vldlr.S Protein
    背景
    The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the lowdensity-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-densitylipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein. It is also one of the receptors of reelin, an extracellular matrix protein which regulates the processes of neuronal migration and synaptic plasticity. In humans, the VLDL-R is encoded by the VLDLR gene. A rare neurological disorder first described in the 1970s under the name "disequilibrium syndrome" is now considered to be caused by the disruption of VLDLR gene. The disorder was renamed VLDLR-associated cerebellar hypoplasia (VLDLRCH) after a 2005 study. It is associated with parental consanguinity and found in secluded communities such as the Hutterites. VLDLRCH is one of the two known genetic disorders caused by a disruption of reelin signaling pathway, along with Norman-Roberts syndrome.
    分子量
    86 kDa
    基因ID
    7436
    UniProt
    P98155
    途径
    Cellular Response to Molecule of Bacterial Origin
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