VLDLR Protein (AA 28-769) (His tag)
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- 抗原 See all VLDLR 蛋白
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 28-769
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VLDLR protein is labelled with His tag.
- 序列
- AA 28-769
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product VLDLR 蛋白
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Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag)
VLDLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag)VLDLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag)Crystallography grade VLDLR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-873) protein (rho-1D4 tag)Crystallography grade VLDLR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- 抗原
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- 别名
- VLDL R (VLDLR 产品)
- 别名
- CARMQ1 Protein, CHRMQ1 Protein, VLDLRCH Protein, AA408956 Protein, AI451093 Protein, AW047288 Protein, vldlr Protein, very low density lipoprotein receptor Protein, very low density lipoprotein receptor S homeolog Protein, VLDLR Protein, Vldlr Protein, vldlr.S Protein
- 背景
- The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the lowdensity-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-densitylipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein. It is also one of the receptors of reelin, an extracellular matrix protein which regulates the processes of neuronal migration and synaptic plasticity. In humans, the VLDL-R is encoded by the VLDLR gene. A rare neurological disorder first described in the 1970s under the name "disequilibrium syndrome" is now considered to be caused by the disruption of VLDLR gene. The disorder was renamed VLDLR-associated cerebellar hypoplasia (VLDLRCH) after a 2005 study. It is associated with parental consanguinity and found in secluded communities such as the Hutterites. VLDLRCH is one of the two known genetic disorders caused by a disruption of reelin signaling pathway, along with Norman-Roberts syndrome.
- 分子量
- 84.0 kDa
- 途径
- Cellular Response to Molecule of Bacterial Origin
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