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RSPO1 Protein (His tag)

RSPO1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN2566898
发货至: 中国
  • 抗原 See all RSPO1 蛋白
    RSPO1 (R-Spondin 1 (RSPO1))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 6
    • 3
    资源
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This RSPO1 protein is labelled with His tag.
    应用范围
    Western Blotting (WB), ELISA
    产品特性

    Measured by its binding ability in a functional ELISA. Immobilized human RSPO1 at 20 μg/mL (100 μL/well ) can bind human LIMPII with a linear ranger of 31. 25 - 1000 ng/mL.

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product RSPO1 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    RSPO1 (R-Spondin 1 (RSPO1))
    别名
    Rspondin 1 (RSPO1 产品)
    别名
    RGD1565558 Protein, CRISTIN3 Protein, RSPO Protein, R-spondin Protein, Rspondin Protein, wu:fj81e05 Protein, zgc:92153 Protein, R-spondin 1 Protein, Rspo1 Protein, RSPO1 Protein, LOC100049655 Protein, rspo1 Protein
    背景
    R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
    分子量
    27.6 kDa
    基因ID
    284654
    UniProt
    Q2MKA7
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