IRAK1 Protein (AA 618-712) (His tag)
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- 抗原 See all IRAK1 蛋白
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 618-712
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IRAK1 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product IRAK1 蛋白
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Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 194-712) (Active) protein (GST tag)
IRAK1 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 504-712) protein (GST tag)IRAK1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-633) protein (GST tag)IRAK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) protein (GST tag)IRAK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-712) protein (Strep Tag)Crystallography grade IRAK1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-710) protein (Strep Tag)Crystallography grade IRAK1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)IRAK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 mM sodium phosphate, 500 mM NaCl, 25 mM imidazole, 10 % gycerol
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- 别名
- IRAK (IRAK1 产品)
- 别名
- IRAK1 Protein, IRAK Protein, pelle Protein, AA408924 Protein, IRAK-1 Protein, IRAK1-S Protein, Il1rak Protein, Plpk Protein, mPLK Protein, RGD1563841 Protein, interleukin 1 receptor associated kinase 1 Protein, interleukin-1 receptor-associated kinase 1 Protein, IRAK1 Protein, irak1 Protein, Irak1 Protein
- 背景
- Nuclear factor kappa B (NF-?B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-?B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF? and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently (1,2). IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response (3). IRAK mediates a signaling cascade leading to NF-?B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF) (1,4).
- 分子量
- 15 kDa (Calculated)
- 基因ID
- 3654
- OMIM
- 8928535
- UniProt
- P51617
- 途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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