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CD4 Protein (CD4) (AA 24-216) (His tag,Strep II tag)

CD4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant ~90 % WB, ELISA, MS, Neut
产品编号 ABIN2468318
发货至: 中国
  • 抗原 See all CD4 蛋白
    CD4
    蛋白类型
    Recombinant
    产品特性
    AA 24-216
    宿主
    • 30
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 26
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This CD4 protein is labelled with His tag,Strep II tag.
    应用范围
    Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
    纯度
    ~90 %
    Top Product
    Discover our top product CD4 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 mM sodium phosphate, 500 mM NaCl, 25 mM imidazole, 10 % gycerol
    注意事项
    Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    储存条件
    -80 °C
    储存方法
    Store in working aliquots at -70 °C.
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    别名
    cd4 Protein, L3T4 Protein, Ly-4 Protein, CD4mut Protein, W3/25 Protein, p55 Protein, CD4 molecule Protein, carcinoembryonic antigen-related cell adhesion molecule 5 Protein, T-cell surface glycoprotein CD4 Protein, CD4 antigen Protein, Cd4 molecule Protein, CD4 Protein, LOC100125525 Protein, cd4 Protein, Cd4 Protein
    背景
    CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response (1). On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 Molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120 (2). This soluble CD4 fragment (sCD4) will work in HIV neutralization assays at levels comparable to previously published results. The minor upper band seen in the Coomassie blue-stained gel is likely to be due to the presence of uncleaved signal sequence.
    分子量
    27 kDa (Calculated)
    基因ID
    920
    NCBI登录号
    NP_000607
    OMIM
    10835167
    UniProt
    P01730
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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