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CD4 Protein (CD4) (AA 26-396) (Fc Tag,AVI tag,Biotin)

CD4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN5674591
发货至: 中国
  • 抗原 See all CD4 蛋白
    CD4
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 26-396
    宿主
    • 32
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    资源
    • 26
    • 8
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    • 4
    • 2
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    • 1
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    HEK-293 Cells
    标记
    This CD4 protein is labelled with Fc Tag,AVI tag,Biotin.
    品牌
    PrecisionAvi
    序列
    AA 26-396
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 69.7 kDa. As a result of glycosylation, the protein migrates as 80 kDa under reducing (R) condition, and 150 kDa under non-redu
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD4 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    别名
    cd4 Protein, L3T4 Protein, Ly-4 Protein, CD4mut Protein, W3/25 Protein, p55 Protein, CD4 molecule Protein, carcinoembryonic antigen-related cell adhesion molecule 5 Protein, T-cell surface glycoprotein CD4 Protein, CD4 antigen Protein, Cd4 molecule Protein, CD4 Protein, LOC100125525 Protein, cd4 Protein, Cd4 Protein
    背景
    T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
    分子量
    69.7 kDa
    NCBI登录号
    NP_000607
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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