ATG5 Protein (AA 1-275) (His tag)
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- 抗原 See all ATG5 蛋白
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-275
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宿主
- 人, 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ATG5 protein is labelled with His tag.
- 应用范围
- ELISA, Western Blotting (WB), Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product ATG5 蛋白
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ATG5 Autophagy Related 5 (ATG5) (AA 138-275) protein (His-IF2DI Tag)
ATG5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (GST tag)ATG5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
ATG5 Autophagy Related 5 (ATG5) (AA 176-275) protein (GST tag)ATG5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
ATG5 Autophagy Related 5 (ATG5) protein (Myc-DYKDDDDK Tag)ATG5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 1X PBS containing 10 % glycerol
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
- 别名
- ATG5 (ATG5 产品)
- 别名
- APG5 Protein, APG5-LIKE Protein, APG5L Protein, ASP Protein, hAPG5 Protein, ATG5 Protein, CG1643 Protein, DmAtg5 Protein, Dmel\\CG1643 Protein, atg5 Protein, 2010107M05Rik Protein, 3110067M24Rik Protein, AW319544 Protein, Apg5l Protein, Atg5l Protein, C88337 Protein, Paddy Protein, apg5l Protein, zgc:100934 Protein, ATATG5 Protein, AUTOPHAGY 5 Protein, MKP11.20 Protein, MKP11_20 Protein, autophagy related 5 Protein, Autophagy-related 5 Protein, ATG5 autophagy related 5 homolog (S. cerevisiae) Protein, autophagy related 5 L homeolog Protein, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 Protein, autophagy protein Apg5 family Protein, ATG5 Protein, Atg5 Protein, atg5 Protein, atg5.L Protein, APG5 Protein
- 背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). ATG5, another member of the autophagy protein family, forms a conjugate with ATG12 , this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy (4). This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells (5).
- 分子量
- 34 kDa (Calculated)
- 基因ID
- 9474
- OMIM
- 10285391
- UniProt
- A9UGY9
- 途径
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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