DIABLO Protein (AA 56-239) (His tag)
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- 抗原 See all DIABLO 蛋白
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- 蛋白类型
- Recombinant
- 产品特性
- AA 56-239
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DIABLO protein is labelled with His tag.
- 序列
- AA 56-239
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 22 kDa under reducing (R) condition (SDS-PAGE).
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DIABLO 蛋白
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Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 61-239) protein (His-IF2DI Tag)
DIABLO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) protein (T7 tag)DIABLO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 119-218) protein (GST tag)DIABLO 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Second Mitochondria-Derived Activator of Caspase (DIABLO) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DIABLO 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Second Mitochondria-Derived Activator of Caspase (DIABLO) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DIABLO 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 20 mM HEPES, 150 mM NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
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- 抗原
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- 别名
- SMAC (DIABLO 产品)
- 别名
- smac Protein, smac3 Protein, diablo-s Protein, 0610041G12Rik Protein, 1700006L01Rik Protein, AU040403 Protein, Smac Protein, DFNA64 Protein, SMAC Protein, DBO Protein, XSmac Protein, diablo, IAP-binding mitochondrial protein Protein, diablo IAP-binding mitochondrial protein Protein, diablo, IAP-binding mitochondrial protein L homeolog Protein, diablo Protein, Diablo Protein, DIABLO Protein, diablo.L Protein
- 背景
- Diablo homolog, mitochondrial (DIABLO) is also known as direct IAP-binding protein with low pI and second mitochondria-derived activator of caspase (SMAC), which can interact with BIRC2/c-IAP1, BIRC3/c-IAP2, XIAP/BIRC4, BIRC6/bruce and BIRC7/livin. Acting by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP),DIABLO can also promote apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Also, DIABLO inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Furthermore, DIABLO is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.
- 分子量
- 21.7 kDa
- NCBI登录号
- NP_063940
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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