MME Protein (AA 52-750) (Fc Tag)
-
- 抗原 See all MME 蛋白
- MME (Membrane Metallo-Endopeptidase (MME))
- 蛋白类型
- Recombinant
- 产品特性
- AA 52-750
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This MME protein is labelled with Fc Tag.
- 序列
- AA 52-750
- 产品特性
- This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 107.3 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MME 蛋白
-
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)
MME 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)MME 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 53-750) protein (His tag)MME 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 1-750) protein (GST tag)MME 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) protein (Fc Tag)MME 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Membrane Metallo-Endopeptidase (MME) (AA 145-250) protein (GST tag)MME 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) protein (His tag)MME 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)Crystallography grade MME 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)Crystallography grade MME 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Membrane Metallo-Endopeptidase (MME) (AA 2-750) protein (rho-1D4 tag)Crystallography grade MME 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
-
- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- Neprilysin (MME 产品)
- 别名
- CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
- 物质类
- Chemical
- 背景
- Cluster of differentiation 10 (CD10) is also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, and common acute lymphoblastic leukemia antigen (CALLA), is a 90-110- kDa type II transmembrane glycoprotein normally expressed by a variety of tissues, including epithelial cells of the prostate, kidney, intestine, endometrium, adrenal glands, and lung. This zinc-dependent metalloprotease enzyme cleaves peptide bonds on the amino side of hydrophobic residues and inactivates a variety of physiologically active secreted peptides. CD20 is thought to be the rate-limiting degrading enzyme of amyloid β peptide (Aβ) whose abnormal misfolding and aggregation in neural tissue has been implicated in the development of Alzheimer's disease (AD). CD10 is also identified as the common acute lymphoblastic leukemia antigen (CALLA) present on leukemic cells of pre-B phenotype, and thus serves as the most important biomarker in the diagnosis of human acute lymphocytic leukemia (ALL).
- 分子量
- 106.8 kDa
- NCBI登录号
- NP_000893
- 途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
-
