MME Protein (AA 99-330) (Fc Tag)
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Quick Overview for MME Protein (AA 99-330) (Fc Tag) (ABIN6964096)
抗原
See all MME 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 99-330
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标记
- This MME protein is labelled with Fc Tag.
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原理
- Recombinant Human CD10 protein with N-terminal human Fc
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特异性
- HFc(Glu99-Ala330) CD10(Tyr52-Trp750)
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Membrane Metallo-Endopeptidase (MME) (AA 52-750) (Active) protein (His tag)
MME 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Membrane Metallo-Endopeptidase (MME) (AA 52-750) (Active) protein (His tag)MME 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Membrane Metallo-Endopeptidase (MME) (AA 53-750) (Active) protein (His tag)MME 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Membrane Metallo-Endopeptidase (MME) (AA 1-750) protein (GST tag)MME 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) protein (His tag)MME 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)MME 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS
Membrane Metallo-Endopeptidase (MME) (AA 52-750) proteinMME 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- CD10
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背景
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MME,CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP,SFE,Neprilysin
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. -
分子量
- predicted molecular mass of 106.1 kDa after removal of the signal peptide.
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基因ID
- 4311
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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