CD55 Protein (AA 35-353) (His tag)
(1 reference)-
- 抗原 See all CD55 蛋白
- CD55 (Complement Decay-Accelerating Factor (CD55))
- 蛋白类型
- Recombinant
- 产品特性
- AA 35-353
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD55 protein is labelled with His tag.
- 序列
- AA 35-353
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.8 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product CD55 蛋白
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Complement Decay-Accelerating Factor (CD55) (AA 35-353) protein (His tag)
CD55 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 36-350) protein (His tag)CD55 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 35-362) protein (His tag)CD55 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 1-381) protein (GST tag)CD55 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Complement Decay-Accelerating Factor (CD55) (AA 35-134) protein (GST tag)CD55 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Complement Decay-Accelerating Factor (CD55) protein (Fc Tag)CD55 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 82 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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: "Distinct CD55 Isoform Synthesis and Inhibition of Complement-Dependent Cytolysis by Hepatitis C Virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 4, pp. 1127-36, (2017) (PubMed).
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: "Distinct CD55 Isoform Synthesis and Inhibition of Complement-Dependent Cytolysis by Hepatitis C Virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 4, pp. 1127-36, (2017) (PubMed).
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- 抗原
- CD55 (Complement Decay-Accelerating Factor (CD55))
- 别名
- CD55 (CD55 产品)
- 别名
- CR Protein, CROM Protein, DAF Protein, TC Protein, Daf Protein, Daf-GPI Protein, Daf1 Protein, GPI-DAF Protein, CD55 molecule (Cromer blood group) Protein, CD55 molecule, decay accelerating factor for complement Protein, CD55 Protein, Cd55 Protein
- 背景
- CD55 is also known as DAF or decay-accelerating factor, is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. CD55 /DAF is a 70 kDa membrane protein that regulates the complement system on the cell surface. It prevents the assembly of the C3bBb complex (the C3-convertase of the alternative pathway) or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex. This glycoprotein is broadly distributed among hematopoietic and non-hematopoietic cells. It is a determinant for the Cromer blood group system. CD55 is known to bind CD97 via the first SCR. It also binds physiologically-generated C3 convertases with its second and third SCRs. Binding results in an accelerated ""decay"", or dissociation of active C3 convertases, thus blocking the development of C' attack complexes on nonforeign cells. Finally, viruses and bacteria are also known to utilize multiple SCR sites for infection.
- 分子量
- 35.8 kDa
- NCBI登录号
- NP_000565
- 途径
- Complement System, Regulation of Leukocyte Mediated Immunity
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