CD55 Protein (Fc Tag)
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- 抗原 See all CD55 蛋白
- CD55 (Complement Decay-Accelerating Factor (CD55))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This CD55 protein is labelled with Fc Tag.
- 原理
- Recombinant Rat CD55/DAF Protein (Fc Tag)
- 序列
- Met1-Ser371
- 产品特性
- A DNA sequence encoding the rat CD55 (Q9Z0M0) (Met1-Ser371) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 82 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CD55 蛋白
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Complement Decay-Accelerating Factor (CD55) (AA 35-353) protein (His tag)
CD55 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 36-350) protein (His tag)CD55 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 35-362) protein (His tag)CD55 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Decay-Accelerating Factor (CD55) (AA 1-381) protein (GST tag)CD55 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Complement Decay-Accelerating Factor (CD55) (AA 35-134) protein (GST tag)CD55 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Complement Decay-Accelerating Factor (CD55) (AA 35-353) protein (His tag)Crystallography grade CD55 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Complement Decay-Accelerating Factor (CD55) (AA 35-362) protein (His tag)Crystallography grade CD55 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD55 (Complement Decay-Accelerating Factor (CD55))
- 别名
- CD55/DAF (CD55 产品)
- 别名
- CR Protein, CROM Protein, DAF Protein, TC Protein, Daf Protein, Daf-GPI Protein, Daf1 Protein, GPI-DAF Protein, CD55 molecule (Cromer blood group) Protein, CD55 molecule, decay accelerating factor for complement Protein, CD55 Protein, Cd55 Protein
- 背景
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Background: CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. CD55 is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. DAF seems to exert different functions beyond its immunological role such as promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection. This 70-75 kDa glycoprotein CD55 containing four SCR modules is involved in the regulation of the complement cascade. It inhibits complement activation by suppressing the function of C3/C5 convertases, thereby limiting local generation or deposition of C3a/C5a and membrane attack complex (MAC or C5b-9) production. DAF has been identified as a ligand for an activation-associated, seven-transmembrane lymphocyte receptor, CD97, which is a receptor mediating attachment and infection of several viruses and bacteria. In addition, it has been shown that DAF regulates the interplay between complement and T cell immunity in vivo, and thus may be implicated in immune and tumor biology.
Synonym: CD55,DAF,Daf1
- 分子量
- 64.5 kDa
- UniProt
- Q9Z0M0
- 途径
- Complement System, Regulation of Leukocyte Mediated Immunity
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