CD44 Protein (CD44) (AA 21-220) (Fc Tag)
(1 reference)-
- 抗原 See all CD44 蛋白
- CD44
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-220
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD44 protein is labelled with Fc Tag.
- 序列
- AA 21-220
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 48.7 kDa. The predicted N-terminus is Gln 21. The reducing (R) protein migrates as 76 kDa in SDS-PAGE due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD44 蛋白
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CD44 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "Impact of structurally modifying hyaluronic acid on CD44 interaction." in: Journal of materials chemistry. B, Vol. 5, Issue 41, pp. 8183-8192, (2017) (PubMed).
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: "Impact of structurally modifying hyaluronic acid on CD44 interaction." in: Journal of materials chemistry. B, Vol. 5, Issue 41, pp. 8183-8192, (2017) (PubMed).
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- 抗原
- CD44
- 别名
- CD44 (CD44 产品)
- 别名
- CDW44 Protein, CSPG8 Protein, ECMR-III Protein, HCELL Protein, HUTCH-I Protein, IN Protein, LHR Protein, MC56 Protein, MDU2 Protein, MDU3 Protein, MIC4 Protein, Pgp1 Protein, AU023126 Protein, AW121933 Protein, AW146109 Protein, HERMES Protein, Ly-24 Protein, Pgp-1 Protein, CD44A Protein, METAA Protein, RHAMM Protein, XCD44 Protein, cd44 Protein, cdw44 Protein, cspg8 Protein, ecmr-iii Protein, hcell Protein, lhr Protein, mc56 Protein, mdu2 Protein, mdu3 Protein, mic4 Protein, mutch-i Protein, pgp1 Protein, CD44 molecule (Indian blood group) Protein, syndecan 4 Protein, CD44 antigen Protein, CD44 molecule (Indian blood group) S homeolog Protein, CD44 Protein, SDC4 Protein, Cd44 Protein, cd44.S Protein
- 背景
- CD44 antigen is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.
- 分子量
- 48.7 kDa
- 途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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