CD44 蛋白
(CD44)
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CD44 Protein (CD44) (AA 1-699) (GST tag) | 人 | 小麦胚 |
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| CD44 Protein (CD44) (AA 21-220) (His tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (AA 152-311) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| CD44 Protein (CD44) (AA 1-361) (GST tag) | 人 | 小麦胚 |
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| CD44 Protein (CD44) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CD44 Protein (CD44) (AA 21-220) (Fc Tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (Fc Tag,His tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (AA 21-220) (His tag) | Cynomolgus | HEK-293 Cells |
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| CD44 Protein (CD44) (AA 21-220) (hIgG-His-tag) | 人 | Baculovirus infected Insect Cells |
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| CD44 Protein (CD44) (AA 21-220) (Fc Tag) | 人 | 人细胞 |
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| CD44 Protein (CD44) (AA 21-649) (His tag) | 人 | Mammalian Cells |
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| CD44 Protein (CD44) (AA 21-742, full length) (His tag,Twin-Strep tag) | 人 | Mammalian Cells |
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| CD44 Protein (CD44) (AA 24-182) (SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| CD44 Protein (CD44) (AA 24-182) (TRX tag) | 人 | 大肠杆菌（E. Coli） |
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| CD44 Protein (CD44) | 人 | 小麦胚 |
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| CD44 Protein (CD44) (AA 21-220) (Fc Tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (AA 21-606, Extracellular, Isoform 4) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| CD44 Protein (CD44) (Transcript Variant 2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| CD44 Protein (CD44) (Transcript Variant 1) (His tag) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
2 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- 宿主
- 人
- 宿主
- 人细胞
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 85 % as determined by SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- AP (Affinity Purification: 所列应用)
- Func (Functional Studies: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
Latest Publications for our CD44 蛋白
: "Biochemical determinants of the IGFBP-3-hyaluronan interaction." in: FEBS open bio, (2020) (PubMed).
: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
: "Impact of structurally modifying hyaluronic acid on CD44 interaction." in: Journal of materials chemistry. B, Vol. 5, Issue 41, pp. 8183-8192, (2017) (PubMed).
: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
: "MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma." in: Molecular cancer therapeutics, Vol. 12, Issue 11, pp. 2446-58, (2013) (PubMed).
: "In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker." in: Nucleic acid therapeutics, Vol. 23, Issue 6, pp. 401-7, (2013) (PubMed).
: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
: "Impact of structurally modifying hyaluronic acid on CD44 interaction." in: Journal of materials chemistry. B, Vol. 5, Issue 41, pp. 8183-8192, (2017) (PubMed).
: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
: "MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma." in: Molecular cancer therapeutics, Vol. 12, Issue 11, pp. 2446-58, (2013) (PubMed).
: "In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker." in: Nucleic acid therapeutics, Vol. 23, Issue 6, pp. 401-7, (2013) (PubMed).
Aliases for CD44 蛋白
CD44 molecule (Indian blood group) (CD44) 蛋白syndecan 4 (SDC4) 蛋白
CD44 antigen (Cd44) 蛋白
CD44 molecule (Indian blood group) (Cd44) 蛋白
CD44 molecule (Indian blood group) S homeolog (cd44.S) 蛋白
AU023126 蛋白
AW121933 蛋白
AW146109 蛋白
cd44 蛋白
CD44A 蛋白
CDW44 蛋白
cdw44 蛋白
CSPG8 蛋白
cspg8 蛋白
ECMR-III 蛋白
ecmr-iii 蛋白
HCELL 蛋白
hcell 蛋白
HERMES 蛋白
HUTCH-I 蛋白
IN 蛋白
LHR 蛋白
lhr 蛋白
Ly-24 蛋白
MC56 蛋白
mc56 蛋白
MDU2 蛋白
mdu2 蛋白
MDU3 蛋白
mdu3 蛋白
METAA 蛋白
MIC4 蛋白
mic4 蛋白
mutch-i 蛋白
Pgp-1 蛋白
Pgp1 蛋白
pgp1 蛋白
RHAMM 蛋白
XCD44 蛋白
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