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ADAM8 Protein (AA 17-497) (His tag)

ADAM8 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN2180563
发货至: 中国
  • 抗原 See all ADAM8 蛋白
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    蛋白类型
    Recombinant
    产品特性
    AA 17-497
    宿主
    • 8
    • 5
    • 2
    资源
    • 6
    • 5
    • 4
    HEK-293 Cells
    标记
    This ADAM8 protein is labelled with His tag.
    序列
    AA 17-497
    产品特性
    rh ADAM8 fused with a polyhistidine tag at the C-terminus, has a calculated MW of 71.6 kDa, which migrates as a 120-150 kDa band in DTT-reduced SDS-PAGE due to glycosylation. Two main fragments bands are visible with apparent MW of 67 kDa and 46 kDa respectively in reduced SDS-PAGE as a result of its being prone to proteolytic cleavage.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ADAM8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50  mM Tris, 150  mM NaCl, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
  • 抗原
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    别名
    ADAM8 (ADAM8 产品)
    别名
    CD156 Protein, MS2 Protein, CD156a Protein, E430039A18Rik Protein, adam8 Protein, reprolysin Protein, si:zc217g15.7 Protein, zgc:64059 Protein, ADAM8 Protein, RGD1566394 Protein, ADAM metallopeptidase domain 8 Protein, a disintegrin and metalloproteinase domain 8 Protein, a disintegrin and metallopeptidase domain 8 Protein, ADAM metallopeptidase domain 8a Protein, ADAM8 Protein, LOC100304737 Protein, Adam8 Protein, adam8a Protein, adam8 Protein
    背景
    Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
    分子量
    53.8 kDa
    途径
    Activation of Innate immune Response, M Phase
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