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ADAM8 Protein (AA 17-658) (His tag)

ADAM8 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273803
发货至: 中国
  • 抗原 See all ADAM8 蛋白
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    蛋白类型
    Recombinant
    产品特性
    AA 17-658
    宿主
    • 9
    • 4
    • 2
    小鼠
    资源
    • 6
    • 5
    • 4
    HEK-293 Cells
    标记
    This ADAM8 protein is labelled with His tag.
    原理
    Mouse ADAM8 Protein
    序列
    Pro17-Ser658
    产品特性
    Recombinant Mouse ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro17-Ser658.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product ADAM8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    别名
    ADAM8 (ADAM8 产品)
    别名
    CD156 Protein, MS2 Protein, CD156a Protein, E430039A18Rik Protein, adam8 Protein, reprolysin Protein, si:zc217g15.7 Protein, zgc:64059 Protein, ADAM8 Protein, RGD1566394 Protein, ADAM metallopeptidase domain 8 Protein, a disintegrin and metalloproteinase domain 8 Protein, a disintegrin and metallopeptidase domain 8 Protein, ADAM metallopeptidase domain 8a Protein, ADAM8 Protein, LOC100304737 Protein, Adam8 Protein, adam8a Protein, adam8 Protein
    背景
    A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer.
    分子量
    71.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa and 35-45 kDa based on Tris-Bis PAGE result.
    UniProt
    Q05910
    途径
    Activation of Innate immune Response, M Phase
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