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C8G Protein (AA 21-202) (His tag)

C8G 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN2115448
发货至: 中国
  • 抗原 See all C8G 蛋白
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    蛋白类型
    Recombinant
    产品特性
    AA 21-202
    宿主
    • 4
    • 1
    • 1
    资源
    • 5
    • 1
    大肠杆菌(E. Coli)
    标记
    This C8G protein is labelled with His tag.
    原理
    Recombinant Human Complement Component C8 γ Chain/C8G (N-6His)
    序列
    MGSSHHHHHH SSGLVPRGSH MQKPQRPRRP ASPISTIQPK ANFDAQQFAG TWLLVAVGSA CRFLQEQGHR AEATTLHVAP QGTAMAVSTF RKLDGICWQV RQLYGDTGVL GRFLLQARGA RGAVNVVVAE TDYQSFAVLY LERAGQLSVK LYARSLPVSD SVLSGFEQRV QEAHLTEDQI FYFPKYGFCE AADQFHVLDE VRR
    产品特性
    Recombinant Human C8G is produced with our E. coli expression system. The target protein is expressed with sequence (Gln21-Arg202) of Human C8G fused with a polyhistidine tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product C8G 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    别名
    Complement Component C8 gamma Chain (C8G 产品)
    别名
    C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein
    背景
    Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
    Synonyms: Complement component C8 gamma chain,C8G
    分子量
    22.6kDa
    UniProt
    P07360
    途径
    Complement System
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