C8G Protein (His tag)
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- 抗原 See all C8G 蛋白
- C8G (Complement Component 8, gamma Polypeptide (C8G))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This C8G protein is labelled with His tag.
- 原理
- Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag)
- 序列
- Gln21-Arg202
- 产品特性
- Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C8G 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- C8G (Complement Component 8, gamma Polypeptide (C8G))
- 别名
- Complement Component C8 Gamma Chain/C8G (C8G 产品)
- 别名
- C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein
- 背景
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Background: Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
Synonym: Complement component C8 gamma chain,C8G
- 分子量
- 22.6 kDa
- UniProt
- P07360
- 途径
- Complement System
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