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C8G Protein (His tag)

C8G 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318327
发货至: 中国
  • 抗原 See all C8G 蛋白
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 4
    • 1
    大肠杆菌(E. Coli)
    标记
    This C8G protein is labelled with His tag.
    原理
    Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag)
    序列
    Gln21-Arg202
    产品特性
    Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product C8G 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    别名
    Complement Component C8 Gamma Chain/C8G (C8G 产品)
    别名
    C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein
    背景

    Background: Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.

    Synonym: Complement component C8 gamma chain,C8G

    分子量
    22.6 kDa
    UniProt
    P07360
    途径
    Complement System
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