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TNFRSF1A Protein (AA 50-201)

TNFRSF1A 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018405
发货至: 中国
  • 抗原 See all TNFRSF1A 蛋白
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 50-201
    宿主
    • 27
    • 14
    • 5
    • 1
    • 1
    • 1
    资源
    • 15
    • 14
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    CHO Cells
    产品特性
    ED50 < 50 ng/mL, measured in a cell proliferation assay using 929 cells in the presence of 1 ng/mL human TNF-a.
    纯度
    > 95 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product TNFRSF1A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Human TNF Receptor Type I remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TNF Receptor Type I should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    别名
    TNF Receptor Type I (TNFRSF1A 产品)
    别名
    CD120a Protein, FPF Protein, MS5 Protein, TBP1 Protein, TNF-R Protein, TNF-R-I Protein, TNF-R55 Protein, TNFAR Protein, TNFR1 Protein, TNFR1-d2 Protein, TNFR55 Protein, TNFR60 Protein, p55 Protein, p55-R Protein, p60 Protein, TNF-R1 Protein, TNF-alphaR1 Protein, TNFRI Protein, TNFRp55 Protein, TNFalpha-R1 Protein, Tnfr-2 Protein, Tnfr1 Protein, fpf Protein, tbp1 Protein, p55-r Protein, tnf-r Protein, tnfar Protein, tnfr1 Protein, cd120a Protein, tnfr55 Protein, tnfr60 Protein, xtnfr1 Protein, wu:fj65b10 Protein, zgc:85914 Protein, TNFR I Protein, TNFRSF1A Protein, TNFA Protein, cTNF Protein, TNF receptor superfamily member 1A Protein, tumor necrosis factor receptor superfamily, member 1a Protein, TNF receptor superfamily member 1A S homeolog Protein, tumor necrosis factor Protein, TNFRSF1A Protein, Tnfrsf1a Protein, tnfrsf1a.S Protein, tnfrsf1a Protein, TNF Protein
    背景
    TNF Receptor Type I, is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-kappaB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells, induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyer's patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli.
    Synonyms: Soluble Tumor Necrosis Factor type I, TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120a
    分子量
    28-35 kDa, observed by reducing SDS-PAGE.
    UniProt
    P19438
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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