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CD25 Protein (AA 22-213) (His tag)

IL2RA 宿主: 人 宿主: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018091
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 蛋白
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-213
    宿主
    • 22
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 15
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293T Cells
    标记
    This CD25 protein is labelled with His tag.
    产品特性
    Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/mL of recombinant IL-2, ED50 for this effect is < 1.5 μg/mL.
    AA 22-213, expressed with N-terminal 8xHis
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL2RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Human Interleukin-2 Receptor alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 Receptor alpha should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    Interleukin-2 Receptor Alpha(IL-2 R Alpha) (IL2RA 产品)
    别名
    CD25 Protein, IDDM10 Protein, IL2R Protein, TCGFR Protein, IL2RAC Protein, IL-2RA Protein, Il2r Protein, Ly-43 Protein, interleukin 2 receptor subunit alpha Protein, interleukin-2 receptor subunit alpha-like Protein, interleukin 2 receptor, alpha chain Protein, IL2RA Protein, Il2ra Protein, LOC100222957 Protein
    背景
    Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to the cytokine IL-2. The IL-2R is made up of 3 subunits - alpha , beta and gamma . The alpha and beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the gamma-chain, along with the beta subunit. The beta and gamma chains of the IL-2R are members of the type I cytokine receptor family. IL-2R has a high binding affinity to IL-2 and is expressed by antigen-activated T lymphocytes (T cells). IL-2 R alpha is also known as CD25, p55, and Tac (activated T cell) antigen.Recombinant Human Interleukin-2 Receptor alpha (IL-2 R alpha), His produced in HEK 293 cells is a polypeptide chain containing 205 amino acids. A fully biologically active molecule, rhIL-2 R alpha has a molecular mass of 42 kDa analyzed by reducing SDS-PAGE.
    Synonyms: soluble IL-2 receptor, TAC-antigen, CD25 antigen
    分子量
    42 kDa, observed by reducing SDS-PAGE.
    UniProt
    P01589
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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