IGFBP4 Protein (AA 22-258) (His tag)
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- 抗原 See all IGFBP4 蛋白
- IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-258
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宿主
- 人
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资源
- HEK-293T Cells
- 标记
- This IGFBP4 protein is labelled with His tag.
- 产品特性
- ED50 < 50 ng/mL, measured in a bioassay using FDC-P1 cells in the presence of 15 ng/mL human IGF-II.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product IGFBP4 蛋白
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Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) (AA 1-258) protein (GST tag)
IGFBP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) (AA 22-258) protein (His tag)Crystallography grade IGFBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) (AA 22-254) protein (His tag)Crystallography grade IGFBP4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human IGF-BP-4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human IGF-BP-4, His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
- 别名
- Insulin-Like Growth Factor-Binding Protein 4 (IGF-BP-4) (IGFBP4 产品)
- 别名
- IGFBP4 Protein, igfbp4 Protein, BP-4 Protein, HT29-IGFBP Protein, IBP4 Protein, IGFBP-4 Protein, AI875747 Protein, Deb2 Protein, IGF-BP4 Protein, IBP-4 Protein, insulin like growth factor binding protein 4 Protein, insulin-like growth factor-binding protein 4 Protein, insulin-like growth factor binding protein 4 Protein, IGFBP4 Protein, LOC100136305 Protein, LOC100194498 Protein, igfbp4 Protein, Igfbp4 Protein
- 背景
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Insulin-like growth factor-binding protein 4 (IGF-BP-4), also known as IBP-4, is a secreted glycoprotein belonging to the IGFBP family. IGF-BP-4 is produced by osteoblasts, epidermis, ovarian follicles and other tissues. It binds both insulin-like growth factor (IGF) I and II, and it circulates in the plasma in both glycosylated and non-glycosylated forms. IGF-BP-4 prolongs the half-life of the IGFs and has been shown to inhibit or stimulate the growth-promoting effects of the IGFs. Pregnancy Associated Plasma Protein A (PAPP-A) proteolytically cleaves IGF-BP-4 and reduces its affinity to bind IGFs, and thus serves as an important regulator of IGF-BP-4 function.
Synonyms: Insulin-like Growth Factor-Binding Protein 4, IBP-4, HT29-IGF-BP, colon cancer cell growth inhibitor - 分子量
- 30-35 kDa, observed by reducing SDS-PAGE.
- UniProt
- P22692
- 途径
- WNT signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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