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IGFBP4 Protein (His tag)

IGFBP4 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318629
发货至: 中国
  • 抗原 See all IGFBP4 蛋白
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    资源
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This IGFBP4 protein is labelled with His tag.
    原理
    Recombinant Human IGFBP-4/IGFBP4 Protein (His Tag)
    序列
    Asp22-Glu258
    产品特性
    Recombinant Human Insulin-Like Growth Factor-Binding Protein 4 is produced by our Mammalian expression system and the target gene encoding Asp22-Glu258 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IGFBP4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    别名
    IGFBP-4/IGFBP4 (IGFBP4 产品)
    别名
    IGFBP4 Protein, igfbp4 Protein, BP-4 Protein, HT29-IGFBP Protein, IBP4 Protein, IGFBP-4 Protein, AI875747 Protein, Deb2 Protein, IGF-BP4 Protein, IBP-4 Protein, insulin like growth factor binding protein 4 Protein, insulin-like growth factor-binding protein 4 Protein, insulin-like growth factor binding protein 4 Protein, IGFBP4 Protein, LOC100136305 Protein, LOC100194498 Protein, igfbp4 Protein, Igfbp4 Protein
    背景

    Background: Insulin-like growth factor binding protein 4 (IGFBP-4) is a 24 kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. All members of the IGFBP family can bind IGF-I and IGF-II with about equal affinity, but IGFBP-4 binds IGF2 more than IGF1. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain. IGFBP-4 is induced by forskolin and N6, O2'dibutyryl sdenosine 3', or 5'-cyclic monophosphate. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

    Synonym: Insulin-Like Growth Factor-Binding Protein 4, IBP-4, IGF-Binding Protein 4, IGFBP-4, IGFBP4, IBP4

    分子量
    27.0 kDa
    UniProt
    P22692
    途径
    WNT signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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