Cathepsin D Protein (CTSD) (AA 21-410) (His tag)
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- 抗原 See all Cathepsin D (CTSD) 蛋白
- Cathepsin D (CTSD)
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-410
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This Cathepsin D protein is labelled with His tag.
- 原理
- Recombinant Mouse Cathepsin D/CSTD (C-6His)
- 序列
- IIRIPLRKFT SIRRTMTEVG GSVEDLILKG PITKYSMQSS PKTTEPVSEL LKNYLDAQYY GDIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KILDIACWVH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC KSDQSKARGI KVEKQIFGEA TKQPGIVFVA AKFDGILGMG YPHISVNNVL PVFDNLMQQK LVDKNIFSFY LNRDPEGQPG GELMLGGTDS KYYHGELSYL NVTRKAYWQV HMDQLEVGNE LTLCKGGCEA IVDTGTSLLV GPVEEVKELQ KAIGAVPLIQ GEYMIPCEKV SSLPTVYLKL GGKNYELHPD KYILKVSQGG KTICLSGFMG MDIPPPSGPL WILGDVFIGS YYTVFDRDNN RVGFANAVVL VDHHHHHH
- 产品特性
- Recombinant Mouse Cathepsin D is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ile21-Leu410) of Mouse Cathepsin D fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CTSD 蛋白
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Cathepsin D (CTSD) (AA 26-412) protein (GST tag)
CTSD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin D (CTSD) protein (His tag)CTSD 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cathepsin D (CTSD) (AA 67-403), (partial) protein (GST tag)CTSD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- Cathepsin D (CTSD)
- 别名
- Cathepsin D (CTSD 产品)
- 别名
- catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
- Sub Type
- Fusionprotein
- 背景
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CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
Alternative Names: Cathepsin D, also known as CTSD and CPSD, is a member of the peptidase A1 family. - 分子量
- 43.9 kDa
- UniProt
- P18242
- 途径
- Peptide Hormone Metabolism
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