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Cathepsin D Protein (CTSD) (His tag)

CTSD 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320739
发货至: 中国
  • 抗原 See all Cathepsin D (CTSD) 蛋白
    Cathepsin D (CTSD)
    蛋白类型
    Recombinant
    宿主
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This Cathepsin D protein is labelled with His tag.
    原理
    Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
    序列
    Ile21-Leu410
    产品特性
    Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSD 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Cathepsin D (CTSD)
    别名
    Cathepsin D/CTSD (CTSD 产品)
    别名
    catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
    背景

    Background: CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.

    Synonym: Cathepsin D, CTSD,CPSD

    分子量
    43.9 kDa
    NCBI登录号
    NP_034113
    途径
    Peptide Hormone Metabolism
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