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Cathepsin D 产品

(Cathepsin D (CTSD))

Categories

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008].

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Featured Cathepsin D Categories

Cathepsin D 抗体

High quality antibodies with extensive validation data.

Cathepsin D ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Cathepsin D 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cathepsin D 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB, IHC (p), IF, IHC (fro), IEM
Validations
  • (1)
  • (12)
Cat. No. ABIN6254162
Quantity 600 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7433375
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (6)
Cat. No. ABIN514771
Quantity 100 μL
Datasheet Datasheet

Recommended Cathepsin D ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
Cat. No. ABIN6574268
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6574269
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963118
Quantity 96 tests
Datasheet Datasheet

Recommended Cathepsin D 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350708
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320739
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090569
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Cathepsin D Products

Ding, Goossens, Oligschlaeger, Houben, Blaak, Shiri-Sverdlov: "Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans." in: Diabetologia, Vol. 63, Issue 2, pp. 374-384, (2020) (PubMed).

Ullrich, Aßmus, Augustin, Häbich, Abeßer, Martin Machado, Werner, Erkens, Arias-Loza, Umbenhauer, Wagner, Benz, Unger, Linke, Frantz, Baba, Kuhn, Schuh: "SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy." in: Journal of molecular and cellular cardiology, Vol. 129, pp. 13-26, (2019) (PubMed).

Lee, Bazick, Chittoor-Vinod, Al Salihi, Xia, Notterpek: "Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients." in: The American journal of pathology, Vol. 188, Issue 3, pp. 728-738, (2019) (PubMed).

Necchi, Sommi, Vanoli, Fiocca, Ricci, Solcia: "Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: vacuoles and beyond." in: Scientific reports, Vol. 7, Issue 1, pp. 14526, (2018) (PubMed).

Oldoni, van Capelleveen, Dalila, Wolters, Heeren, Sinke, Hui, Dallinga-Thie, Frikke-Schmidt, Hovingh, van de Sluis, Tybjærg-Hansen, Kuivenhoven et al.: "Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger ..." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 7, pp. 1440-1453, (2018) (PubMed).

Wu, Sun, Ma, Zhu, Zhang, Pan, Li, Liu, Diao, Li: "A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum." in: Scientific reports, Vol. 6, pp. 27332, (2018) (PubMed).

Liu, Chen, Zhang, Tan, Wang: "Increased Cathepsin D Correlates with Clinical Parameters in Newly Diagnosed Type 2 Diabetes." in: Disease markers, Vol. 2017, pp. 5286408, (2018) (PubMed).

Ahlemeyer, Halupczok, Rodenberg-Frank, Valerius, Baumgart-Vogt: "Endogenous Murine Amyloid-β Peptide Assembles into Aggregates in the Aged C57BL/6J Mouse Suggesting These Animals as a Model to Study Pathogenesis of Amyloid-β Plaque Formation." in: Journal of Alzheimer's disease : JAD, Vol. 61, Issue 4, pp. 1425-1450, (2017) (PubMed).

Sedaghat, Taab, Kiasalari, Afshin-Majd, Baluchnejadmojarad, Roghani: "Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms." in: Biomedicine & pharmacotherapy, Vol. 87, pp. 200-208, (2017) (PubMed).

Zheng, Li, Wang, Wang, Liao, Hu, Fan, Kang, Zeng, Wu, Wu, Zhang, Wang, He et al.: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).

Synonyms and alternative names related to Cathepsin D

cathepsin D (ctsd), cathepsin D (LOC398557), cathepsin D S homeolog (ctsd.S), cathepsin D (CatD), lysosomal aspartic protease (LOC5567565), cathepsin D (LOC100136761), cathepsin D (CTSD), cathepsin D (Cathd), cathepsin D (ctsD), cathepsin D (catd), cathepsin D (Ctsd), cathepsin D-like (LOC443060), catD, CatD, Cathd, CD, CLN10, CPSD, CTSD, DDBDRAFT_0205785, DDBDRAFT_0215012, DDB_0205785, DDB_0215012, DKFZp469J0315, fb93e11, fj17b09, LOC398557, LOC100136761, wu:fb93e11, wu:fj17b09

Protein level used designations for Cathepsin D

  • etID16901.18
  • cathepsin D
  • aspartic protease
  • cathepsin d
  • preprocathepsin D
  • ceroid-lipofuscinosis, neuronal 10
  • lysosomal aspartyl peptidase
  • lysosomal aspartyl protease
  • cathepsin D (lysosomal aspartyl peptidase)
  • cathepsin D (lysosomal aspartyl protease)
  • prepro-cathepsin D, prepro-CD
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