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ATG4A Protein (AA 1-398) (His tag)

ATG4A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1692089
发货至: 中国
  • 抗原 See all ATG4A 蛋白
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    蛋白类型
    Recombinant
    产品特性
    AA 1-398
    宿主
    • 4
    • 2
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This ATG4A protein is labelled with His tag.
    原理
    Recombinant Human Autophagy Related 4 Homolog A/ATG4A (N-6His)
    序列
    MGSSHHHHHH SSGLVPRGSH MESVLSKYED QITIFTDYLE EYPDTDELVW ILGKQHLLKT EKSKLLSDIS ARLWFTYRRK FSPIGGTGPS SDAGWGCMLR CGQMMLAQAL ICRHLGRDWS WEKQKEQPKE YQRILQCFLD RKDCCYSIHQ MAQMGVGEGK SIGEWFGPNT VAQVLKKLAL FDEWNSLAVY VSMDNTVVIE DIKKMCRVLP LSADTAGDRP PDSLTASNQS KGTSAYCSAW KPLLLIVPLR LGINQINPVY VDAFKECFKM PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF HCLQSPQRMN ILNLDPSVAL GFFCKEEKDF DNWCSLVQKE ILKENLRMFE LVQKHPSHWP PFVPPAKPEV TTTGAEFIDS TEQLEEFDLE EDFEILSV
    产品特性

    Recombinant Human Autophagy Related 4 Homolog A/ATG4A (N-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ATG4A 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    别名
    Autophagy Related 4 Homolog A (ATG4A 产品)
    别名
    apg4a Protein, autl2 Protein, F6E13.27 Protein, APG4A Protein, zgc:111958 Protein, Aut2a Protein, AUTL2 Protein, AI627006 Protein, AV169859 Protein, Apg4a Protein, Atg4al Protein, Autl2 Protein, Atg4a Protein, autophagy related 4A cysteine peptidase L homeolog Protein, autophagy related 4A cysteine peptidase Protein, Peptidase family C54 protein Protein, ATG4 autophagy related 4 homolog A (S. cerevisiae) Protein, autophagy related 4A, cysteine peptidase Protein, atg4a.L Protein, ATG4A Protein, AT2G44140 Protein, atg4a Protein, Atg4a Protein
    背景
    Recombinant Human Cysteine Protease ATG4A/ATG4A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Val398) of Human ATG4A fused with a 6His tag at the N-terminus.
    Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy, it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
    分子量
    47.5 kDa
    UniProt
    Q8WYN0
    途径
    Autophagy
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