ATG4A 产品
(Autophagy related 4A Cysteine Peptidase (ATG4A))
Categories
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured ATG4A Categories
Recommended ATG4A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (5)
Cat. No.
ABIN7193210
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (4)
Cat. No.
ABIN7193211
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN3023409
Quantity
100 μL
Datasheet
Datasheet
Recommended ATG4A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951537
Quantity
96 tests
Datasheet
Datasheet
Recommended ATG4A 蛋白
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Reactivity
Source
Validations
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Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121951
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345970
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3089493
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ATG4A Products
: "MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells." in: PLoS ONE, Vol. 12, Issue 6, pp. e0179772, (2017) (PubMed).: "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
: "Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7327-38, (2011) (PubMed).
: "Autophagy in metazoans: cell survival in the land of plenty." in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 439-48, (2005) (PubMed).
: "Autophagy: dual roles in life and death?" in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 505-10, (2005) (PubMed).
: "Degrade or die: a dual function for autophagy in the plant immune response." in: Developmental cell, Vol. 8, Issue 6, pp. 799-801, (2005) (PubMed).
: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).
: "The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14053-8, (2003) (PubMed).
Synonyms and alternative names related to ATG4A
autophagy related 4A cysteine peptidase L homeolog (atg4a.L), autophagy related 4A cysteine peptidase (ATG4A), Peptidase family C54 protein (AT2G44140), ATG4 autophagy related 4 homolog A (S. cerevisiae) (atg4a), autophagy related 4A, cysteine peptidase (atg4a), autophagy related 4A, cysteine peptidase (Atg4a), AI627006, apg4a, APG4A, Apg4a, Atg4a, Atg4al, Aut2a, autl2, AUTL2, Autl2, AV169859, F6E13.27, zgc:111958Protein level used designations for ATG4A
- ATG4 autophagy related 4 homolog A
- autophagy-related protein 4 homolog A
- cysteine protease ATG4A
- autophagy-related cysteine endopeptidase 2
- Cysteine protease ATG4A
- autophagin-2A
- autophagy-related cysteine endopeptidase 2A
- bAut2A
- APG4 autophagy 4 homolog A
- AUT-like 2 cysteine endopeptidase
- AUT-like 2, cysteine endopeptidase
- autophagin 2
- autophagin-2
- hAPG4A
- APG4 (ATG4) autophagy-related homolog A
- autophagy 4 homolog A
- autophagy-related 4A
- cysteine protease APG4A
- autophagy related 4 homolog A
- autophagy related 4A, cysteine peptidase
- uncharacterized protein LOC678769
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