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ATOX1 产品

(ATX1 Antioxidant Protein 1 Homolog (ATOX1))

Categories

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008].

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Featured ATOX1 Categories

ATOX1 抗体

High quality antibodies with extensive validation data.

ATOX1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATOX1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN513587
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN513590
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN513591
Quantity 100 μg
Datasheet Datasheet

Recommended ATOX1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951064
Quantity 96 tests
Datasheet Datasheet

Recommended ATOX1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121947
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346008
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Yeast
Validations
Cat. No. ABIN5570175
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ATOX1 Products

Beaino, Guo, Chang, Anderson: "Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapy." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 19, Issue 3, pp. 427-38, (2014) (PubMed).

Flores, Unger: "Atox1 contains positive residues that mediate membrane association and aid subsequent copper loading." in: The Journal of membrane biology, Vol. 246, Issue 12, pp. 903-13, (2013) (PubMed).

Cai, Peng: "Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells." in: Oncology reports, Vol. 30, Issue 1, pp. 269-75, (2013) (PubMed).

Palm, Weise, Lundin, Wingsle, Nygren, Björn, Naredi, Wolf-Watz, Wittung-Stafshede: "Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 17, pp. 6951-6, (2011) (PubMed).

Synonyms and alternative names related to ATOX1

antioxidant 1 copper chaperone (ATOX1), antioxidant 1 copper chaperone (Atox1), Antioxidant 1 copper chaperone (Atox1), antioxidant 1 copper chaperone (atox1), copper transport protein (atox1), ATX1 antioxidant protein 1 homolog (atox1), AI256639, ATOX1, ATX1, Atx1, atx1, CG12562, CG32446, DDBDRAFT_0185901, DDBDRAFT_0266724, DDB_0185901, DDB_0266724, DmAtox1, Dmel\\CG32446, HAH1, hah1, SAH

Protein level used designations for ATOX1

  • ATX1 antioxidant protein 1 homolog
  • copper transport protein ATOX1
  • metal transport protein ATX1
  • copper chaperone
  • Atox1-PA
  • Atox1-PB
  • CG32446-PA
  • CG32446-PB
  • Copper transport protein ATOX1
  • ATX1 (antioxidant protein 1) homolog 1
  • ATX1 homolog protein Rah1
  • copper chaperone SAH
  • ATX1 antioxidant protein 1 homolog (yeast)
  • antioxidant protein 1 homolog
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