STAT1 Protein (AA 1-712)
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- 抗原 See all STAT1 蛋白
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-712
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Signal Transducer and Activator of Transcription 1/STAT1
- 序列
- GSHMSQWYEL QQLDSKFLEQ VHQLYDDSFP MEIRQYLAQW LEKQDWEHAA NDVSFATIRF HDLLSQLDDQ YSRFSLENNF LLQHNIRKSK RNLQDNFQED PIQMSMIIYS CLKEERKILE NAQRFNQAQS GNIQSTVMLD KQKELDSKVR NVKDKVMCIE HEIKSLEDLQ DEYDFKCKTL QNREHETNGV AKSDQKQEQL LLKKMYLMLD NKRKEVVHKI IELLNVTELT QNALINDELV EWKRRQQSAC IGGPPNACLD QLQNWFTIVA ESLQQVRQQL KKLEELEQKY TYEHDPITKN KQVLWDRTFS LFQQLIQSSF VVERQPCMPT HPQRPLVLKT GVQFTVKLRL LVKLQELNYN LKVKVLFDKD VNERNTVKGF RKFNILGTHT KVMNMEESTN GSLAAEFRHL QLKEQKNAGT RTNEGPLIVT EELHSLSFET QLCQPGLVID LETTSLPVVV ISNVSQLPSG WASILWYNML VAEPRNLSFF LTPPCARWAQ LSEVLSWQFS SVTKRGLNVD QLNMLGEKLL GPNASPDGLI PWTRFCKENI NDKNFPFWLW IESILELIKK HLLPLWNDGC IMGFISKERE RALLKDQQPG TFLLRFSESS REGAITFTWV ERSQNGGEPD FHAVEPYTKK ELSAVTFPDI IRNYKVMAAE NIPENPLKYL YPNIDKDHAF GKYYSRPKEA PEPMELDGPK GTGYIKTELI SVSEV
- 产品特性
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Recombinant Human Signal Transducer and Activator of Transcription 1/STAT1
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product STAT1 蛋白
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Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) protein (His tag)
STAT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) protein (GST tag)STAT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) protein (GST tag)STAT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-750) protein (His tag)Crystallography grade STAT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-749) protein (His tag)Crystallography grade STAT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- 别名
- Signal Transducer and Activator of Transcription 1-alpha/beta/stat1 (STAT1 产品)
- 别名
- CANDF7 Protein, ISGF-3 Protein, STAT91 Protein, 2010005J02Rik Protein, AA408197 Protein, XStat1 Protein, STAT4 Protein, DD6G4-4 Protein, STAT Protein, STAT1 Protein, dZ182H3.3 Protein, si:by134g18.2 Protein, si:by51f19.1 Protein, si:dz182h3.3 Protein, si:dz199m19.1 Protein, si:dz73o4.2 Protein, stat1 Protein, signal transducer and activator of transcription 1 Protein, signal transducer and activator of transcription 1 L homeolog Protein, signal transducer and activator of transcription 1, 91kDa Protein, signal transducer and activator of transcription 4 Protein, signal transducer and activator of transcription 1a Protein, STAT1 Protein, Stat1 Protein, stat1.L Protein, stat4 Protein, stat1a Protein
- 背景
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Recombinant Human Signal Transducer and Activator of Transcription 1-α/β/STAT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Val712) of Human STAT1.
Signal Transducer and Activator of Transcription 1-α/β (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-γ-activated factor (GAF), migrate into the nucleus and bind to the IFN γ activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7. - 分子量
- 83.3 kDa
- UniProt
- P42224
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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