STAT1 蛋白
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北京 101111
Quick Overview for STAT1 蛋白 (ABIN7319272)
抗原
See all STAT1 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human STAT1 Protein
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序列
- Met 1-Val712
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产品特性
- Recombinant Human Signal Transducer and Activator of Transcription 1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) protein (His tag)
STAT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) protein (GST tag)STAT1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) protein (GST tag)STAT1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 0.02 % Tween 80, 5 % Sucrose, 4 % Mannitol, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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别名
- STAT1
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背景
- CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT1,STAT91,Signal Transducer and Activator of Transcription 1-Alpha/Beta,Transcription Factor ISGF-3 Components p91/p84,Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
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分子量
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Calculated MW: 83.3 kDa
Observed MW: 85 kDa
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基因ID
- 6772
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UniProt
- P42224
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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