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IRF5 Protein (AA 1-498) (His tag)

IRF5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90% by SDS-PAGE
产品编号 ABIN1691985
发货至: 中国
  • 抗原 See all IRF5 蛋白
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    蛋白类型
    Recombinant
    产品特性
    AA 1-498
    宿主
    • 13
    • 3
    • 1
    资源
    • 7
    • 5
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This IRF5 protein is labelled with His tag.
    原理
    Recombinant Human Interferon Regulatory Factor 5/IRF5 (C-6His)
    序列
    MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA TRHGPSQDGD NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF RLIYDGPRDM PPQPYKIYEV CSNGPAPTDS QPPEDYSFGA GEEEEEEEEL QRMLPSLSLT EDVKWPPTLQ PPTLRPPTLQ PPTLQPPVVL GPPAPDPSPL APPPGNPAGF RELLSEVLEP GPLPASLPPA GEQLLPDLLI SPHMLPLTDL EIKFQYRGRP PRALTISNPH GCRLFYSQLE ATQEQVELFG PISLEQVRFP SPEDIPSDKQ RFYTNQLLDV LDRGLILQLQ GQDLYAIRLC QCKVFWSGPC ASAHDSCPNP IQREVKTKLF SLEHFLNELI LFQKGQTNTP PPFEIFFCFG EEWPDRKPRE KKLITVQVVP VAARLLLEMF SGELSWSADS IRLQISNPDL KDRMVEQFKE LHHIWQSQQR LQPVAQAPPG AGLGVGQGPW PMHPAGMQLE HHHHHH
    产品特性
    Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
    纯度
    >90% by SDS-PAGE
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 1 EU/ug
    Top Product
    Discover our top product IRF5 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, pH8.0
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    别名
    IRF5 (IRF5 产品)
    别名
    IRF5 Protein, irf5 Protein, SLEB10 Protein, AW491843 Protein, mirf5 Protein, im:7155364 Protein, zgc:76986 Protein, interferon regulatory factor 5 Protein, interferon regulatory factor 5 L homeolog Protein, IRF5 Protein, irf5 Protein, Irf5 Protein, irf5.L Protein
    Sub Type
    Fusionprotein
    背景
    Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
    Alternative Names: Interferon Regulatory Factor 5, IRF-5, IRF5
    UniProt
    Q13568
    途径
    TLR signaling, Autophagy
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