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TNFRSF21 Protein (AA 42-349) (Fc Tag,His tag)

TNFRSF21 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691790
发货至: 中国
  • 抗原 See all TNFRSF21 蛋白
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    蛋白类型
    Recombinant
    产品特性
    AA 42-349
    宿主
    • 24
    • 9
    • 1
    小鼠
    资源
    • 10
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This TNFRSF21 protein is labelled with Fc Tag,His tag.
    原理
    Recombinant Mouse Death Receptor 6/DR6/TNFRSF21/CD358 (C-Fc-6His)
    序列
    QPEQKTLSLP GTYRHVDRTT GQVLTCDKCP AGTYVSEHCT NMSLRVCSSC PAGTFTRHEN GIERCHDCSQ PCPWPMIERL PCAALTDREC ICPPGMYQSN GTCAPHTVCP VGWGVRKKGT ENEDVRCKQC ARGTFSDVPS SVMKCKAHTD CLGQNLEVVK PGTKETDNVC GMRLFFSSTN PPSSGTVTFS HPEHMESHDV PSSTYEPQGM NSTDSNSTAS VRTKVPSGIE EGTVPDNTSS TSGKEGTNRT LPNPPQVTHQ QAPHHRHILK LLPSSMEATG EKSSTAIKAP KRGHPRQNAH KHFDINEHVD DIEGRMDEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
    产品特性

    Recombinant Mouse Death Receptor 6/DR6/TNFRSF21/CD358 (C-Fc-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TNFRSF21 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    别名
    Tumor Necrosis Factor Receptor Superfamily Member 21/DR6/TNFRSF21 (TNFRSF21 产品)
    别名
    TNFRSF21 Protein, tnfrsf21 Protein, MGC146356 Protein, BM-018 Protein, CD358 Protein, DR6 Protein, AA959878 Protein, R74815 Protein, TR7 Protein, dr6 Protein, im:6795346 Protein, wu:fa55e01 Protein, wu:fb02e11 Protein, wu:fc29a09 Protein, wu:fi27h08 Protein, TNF receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily, member 21 Protein, TNFRSF21 Protein, tnfrsf21 Protein, Tnfrsf21 Protein
    背景
    Recombinant Mouse Tumor necrosis factor receptor superfamily member 21/DR6/TNFRSF21 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln42-His349) of Mouse TNFRSF21 fused with a FC-6His tag at the C-terminus.
    Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-κB and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by β-secretase to release sAPP-β which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
    分子量
    64.7 kDa
    UniProt
    Q9EPU5
    途径
    Regulation of Lipid Metabolism by PPARalpha
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