TNFRSF21 Protein (His tag)
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- 抗原 See all TNFRSF21 蛋白
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This TNFRSF21 protein is labelled with His tag.
- 原理
- Recombinant Mouse DR6/TNFRSF21 Protein (His Tag)(Active)
- 序列
- Met 1-His 349
- 产品特性
- A DNA sequence encoding the mouse TNFRSF21 (NP_055267.1) extracellular domain (Met 1-His 349) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Immobilized mouse TNFRSF21-His at 10 μg/ml (100 μl/well) can bind biotinylated human APP-Fc with a linear range of 0.31-5 μg/ml.
- Top Product
- Discover our top product TNFRSF21 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)
TNFRSF21 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 89-170) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 47-214) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 47-349) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 373-655) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-472) protein (GST tag)TNFRSF21 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-124) protein (GST tag)TNFRSF21 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-212) proteinTNFRSF21 宿主: 人 宿主: Human Recombinant SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- 别名
- DR6/TNFRSF21 (TNFRSF21 产品)
- 别名
- TNFRSF21 Protein, tnfrsf21 Protein, MGC146356 Protein, BM-018 Protein, CD358 Protein, DR6 Protein, AA959878 Protein, R74815 Protein, TR7 Protein, dr6 Protein, im:6795346 Protein, wu:fa55e01 Protein, wu:fb02e11 Protein, wu:fc29a09 Protein, wu:fi27h08 Protein, TNF receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily, member 21 Protein, TNFRSF21 Protein, tnfrsf21 Protein, Tnfrsf21 Protein
- 背景
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Background: TNFRSF21 (death receptor-6, DR6) is an orphan TNF receptor superfamily member and belongs to a subgroup of receptors called death receptors. This type I transmembrane receptor possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is an extensively posttranslationally modified transmembrane protein and that N- and O-glycosylations of amino acids in its extracellular part. DR6 interacts with the adaptor protein TRADD and mediates signal transduction through its death domain, and expression of DR6 in mammalian cells induces activation of both NF-kappaB and JNK and cell apoptosis. DR6 knockout mice have enhanced CD4+ T cell proliferation and Th2 cytokine production, suggested that DR6 serves as an important regulatory molecule in T-helper cell activation, and is involved in inflammation and immune regulation. DR6 is expressed ubiquitously with high expression in lymphoid organs, heart, brain and pancreas. Some tumor cells overexpress DR6, typically in conjunction with elevated anti-apoptosis molecules. DR6 may also be involved in tumor cell survival and immune evasion, which is subject to future investigations.
Synonym: AA959878 Protein, DR6 Protein, R74815 Protein, TR7 Protein
- 分子量
- 35 kDa
- NCBI登录号
- NP_055267
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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