TNFRSF12A Protein (AA 28-79) (Fc Tag)
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- 抗原 See all TNFRSF12A 蛋白
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 28-79
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This TNFRSF12A protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)
- 序列
- EQAPGTSPCS SGSSWSADLD KCMDCASCPA RPHSDFCLGC AAAPPAHFRL LWVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
- 产品特性
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Recombinant Mouse TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TNFRSF12A 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (Active) protein
TNFRSF12A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) protein (Fc Tag)TNFRSF12A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) protein (Fc Tag)TNFRSF12A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) protein (His tag)TNFRSF12A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) protein (mFc Tag)TNFRSF12A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-129) protein (GST tag)TNFRSF12A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-129) protein (rho-1D4 tag)Crystallography grade TNFRSF12A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-129) protein (rho-1D4 tag)Crystallography grade TNFRSF12A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- 别名
- Tumor Necrosis Factor Receptor Superfamily Member 12A/TWEAKR/TNFRSF12 (TNFRSF12A 产品)
- 别名
- CD266 Protein, FN14 Protein, TWEAKR Protein, AI255180 Protein, C87282 Protein, Fn14 Protein, HPIP Protein, TWEAK-R Protein, TweakR Protein, TNF receptor superfamily member 12A Protein, tumor necrosis factor receptor superfamily, member 12a Protein, TNFRSF12A Protein, Tnfrsf12a Protein
- 背景
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Recombinant Mouse Tumor necrosis factor receptor superfamily member 12A/TWEAKR/TNFRSF12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu28-Trp79) of Mouse TNFRSF12 fused with a FC tag at the C-terminus.
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important role in the inflammatory processes of rheumatoid arthritis (RA), polyarticular-course juvenile rheumatoid arthritis (JRA), and ankylosing spondylitis and the resulting joint pathology. In addition, TNF plays a role in the inflammatory process of plaque psoriasis. Elevated levels of TNF are found in involved tissues and fluids of patients with RA, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Two distinct receptors for TNF (TNFRs), a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75), exist naturally as monomeric molecules on cell surfaces and in soluble forms. Biological activity of TNF is dependent upon binding to either cell surface TNFR. Recombinant Human TNFR is a dimeric soluble form of the p75 TNF receptor that can bind to two TNF molecules. - 分子量
- 32.6 kDa
- UniProt
- Q9CR75
- 途径
- Apoptosis, Regulation of Cell Size
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