ESAM Protein (AA 30-247) (Fc Tag)
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- 抗原 See all ESAM 蛋白
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 蛋白类型
- Recombinant
- 产品特性
- AA 30-247
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宿主
- 人
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资源
- 人细胞
- 标记
- This ESAM protein is labelled with Fc Tag.
- 原理
- Recombinant Human Endothelial Cell Adhesion Molecule/ESAM (C-Fc)
- 序列
- QLQLHLPANR LQAVEGGEVV LPAWYTLHGE VSSSQPWEVP FVMWFFKQKE KEDQVLSYIN GVTTSKPGVS LVYSMPSRNL SLRLEGLQEK DSGPYSCSVN VQDKQGKSRG HSIKTLELNV LVPPAPPSCR LQGVPHVGAN VTLSCQSPRS KPAVQYQWDR QLPSFQTFFA PALDVIRGSL SLTNLSSSMA GVYVCKAHNE VGTAQCNVTL EVSTGPGAVD DIEGRMDEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
- 产品特性
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Recombinant Human Endothelial Cell Adhesion Molecule/ESAM (C-Fc)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ESAM 蛋白
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Endothelial Cell Adhesion Molecule (ESAM) (AA 1-390) protein (GST tag)
ESAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelial Cell Adhesion Molecule (ESAM) protein (His tag)ESAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Endothelial Cell Adhesion Molecule (ESAM) protein (Fc Tag)ESAM 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Endothelial Cell Adhesion Molecule (ESAM) (AA 270-390) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-248) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 273-394) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-251) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-390) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-394) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 别名
- Endothelial Cell Adhesion Molecule/ESAM (ESAM 产品)
- 别名
- ESAM Protein, sc:d0254 Protein, W117m Protein, 2310008D05Rik Protein, Esam1 Protein, endothelial cell adhesion molecule Protein, endothelial cell adhesion molecule a Protein, endothelial cell-specific adhesion molecule Protein, ESAM Protein, esama Protein, Esam Protein
- 背景
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Recombinant Human Endothelial Cell Adhesion Molecule/ESAM is produced by our mammalian expression system. The target protein is expressed with sequence (Gln30-Ala247) of Human ESAM fused with a FC tag at the C-terminus.
Endothelial Cell Adhesion Molecule (ESAM) is a 55 kDa type I transmembrane glycoprotein member of the JAM family of immunoglobulin superfamily molecules. The 390 AA Human ESAM contains a 216 AA extracellular domain (ECD) with a V-type and a C2-type immunoglobulin (Ig) domain. ESAM is specifically expressed at endothelial tight junctions and on activated platelets and performs homophilic adhesion activity. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. In addition, ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. ESAM-deficient mice were described with lowered angiogenic potential, and accordingly, overexpression of ESAM is closely associated with certain tumor growth and metastasis. ESAM is expressed on endothelial cells, activated platelets and megakaryocytes. The ECD of human and mouse ESAM share 69 % AA identity. - 分子量
- 50.8 kDa
- UniProt
- Q96AP7
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