ESAM Protein (Fc Tag)
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- 抗原 See all ESAM 蛋白
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This ESAM protein is labelled with Fc Tag.
- 原理
- Recombinant Rat ESAM Protein (Fc Tag)
- 序列
- Met 1-Ala 251
- 产品特性
- A DNA sequence encoding the rat ESAM (Q6AYD4) extracellular domain (Met 1-Ala 251) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 85 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product ESAM 蛋白
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Endothelial Cell Adhesion Molecule (ESAM) (AA 1-390) protein (GST tag)
ESAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelial Cell Adhesion Molecule (ESAM) protein (His tag)ESAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Endothelial Cell Adhesion Molecule (ESAM) (AA 270-390) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-248) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 273-394) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-251) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-390) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-394) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 别名
- ESAM (ESAM 产品)
- 别名
- ESAM Protein, sc:d0254 Protein, W117m Protein, 2310008D05Rik Protein, Esam1 Protein, endothelial cell adhesion molecule Protein, endothelial cell adhesion molecule a Protein, endothelial cell-specific adhesion molecule Protein, ESAM Protein, esama Protein, Esam Protein
- 背景
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Background: Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
Synonym: ESAM
- 分子量
- 51.2 kDa
- UniProt
- Q6AYD4
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