ESAM Protein (AA 30-247) (His tag)
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- 抗原 See all ESAM 蛋白
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 蛋白类型
- Recombinant
- 产品特性
- AA 30-247
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宿主
- 人
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资源
- 人细胞
- 标记
- This ESAM protein is labelled with His tag.
- 原理
- Recombinant Human ESAM Protein (aa 30-247, His Tag)
- 序列
- Gln30-Ala247
- 产品特性
- Recombinant Human Endothelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln30-Ala247 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ESAM 蛋白
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Endothelial Cell Adhesion Molecule (ESAM) (AA 1-390) protein (GST tag)
ESAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelial Cell Adhesion Molecule (ESAM) protein (His tag)ESAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Endothelial Cell Adhesion Molecule (ESAM) protein (Fc Tag)ESAM 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Endothelial Cell Adhesion Molecule (ESAM) (AA 270-390) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-248) protein (His tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 273-394) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-251) protein (His tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-390) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelial Cell Adhesion Molecule (ESAM) (AA 30-394) protein (rho-1D4 tag)Crystallography grade ESAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ESAM (Endothelial Cell Adhesion Molecule (ESAM))
- 别名
- ESAM (ESAM 产品)
- 别名
- ESAM Protein, sc:d0254 Protein, W117m Protein, 2310008D05Rik Protein, Esam1 Protein, endothelial cell adhesion molecule Protein, endothelial cell adhesion molecule a Protein, endothelial cell-specific adhesion molecule Protein, ESAM Protein, esama Protein, Esam Protein
- 背景
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Background: Endothelial Cell Adhesion Molecule (ESAM) is a 55 kDa type I transmembrane glycoprotein member of the JAM family of immunoglobulin superfamily molecules. The 390 amino acid Human ESAM contains a 216 amino acid extracellular domain (ECD) with a V-type and a C2-type immunoglobulin (Ig) domain. ESAM is specifically expressed at endothelial tight junctions and on activated platelets and performs homophilic adhesion activity. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. In addition, ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. ESAM-deficient mice were described with lowered angiogenic potential, and accordingly, overexpression of ESAM is closely associated with certain tumor growth and metastasis. ESAM is expressed on endothelial cells, activated platelets and megakaryocytes. The ECD of human and mouse ESAM share 69 % amino acid identity.
Synonym: Endothelial Cell-Selective Adhesion Molecule, ESAM
- 分子量
- 24.79 kDa
- UniProt
- Q96AP7
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