Recombinant Human Trem-like transcript 1 protein/TREML1/TLT1 is produced by our mammalian expression system. The target protein is expressed with sequence (Gln16-Pro162) of Human TREML1 fused with a FC tag at the C-terminus.
纯度
> 95 % as determined by reducing SDS-PAGE.
过滤
0.2 μm filtered
内毒素水平
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
TREML1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
溶解方式
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
缓冲液
Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
注意事项
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
储存条件
4 °C/-20 °C/-80 °C
储存方法
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
有效期
5 months
抗原
TREML1
(Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
GLTL1825 Protein, PRO3438 Protein, TLT-1 Protein, TLT1 Protein, dJ238O23.3 Protein, 5430401J17Rik Protein, RGD1565175 Protein, triggering receptor expressed on myeloid cells 2 Protein, triggering receptor expressed on myeloid cells like 1 Protein, triggering receptor expressed on myeloid cells-like 1 Protein, LOC474898 Protein, TREML1 Protein, Treml1 Protein
Sub Type
Fusionprotein
背景
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury. Alternative Names: Trem-Like Transcript 1 Protein, TLT-1, Triggering Receptor Expressed on Myeloid Cells-Like Protein 1, TREML1, TLT1