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TREML1 Protein (His tag)

TREML1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319111
发货至: 中国
  • 抗原 See all TREML1 蛋白
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    资源
    • 5
    • 3
    • 1
    • 1
    人细胞
    标记
    This TREML1 protein is labelled with His tag.
    原理
    Recombinant Human TREML1/TLT-1 Protein (His Tag)
    序列
    Gln16-Pro162
    产品特性
    Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Gln16-Pro162 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TREML1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    别名
    TREML1/TLT-1 (TREML1 产品)
    别名
    GLTL1825 Protein, PRO3438 Protein, TLT-1 Protein, TLT1 Protein, dJ238O23.3 Protein, 5430401J17Rik Protein, RGD1565175 Protein, triggering receptor expressed on myeloid cells 2 Protein, triggering receptor expressed on myeloid cells like 1 Protein, triggering receptor expressed on myeloid cells-like 1 Protein, LOC474898 Protein, TREML1 Protein, Treml1 Protein
    背景

    Background: Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.

    Synonym: Trem-Like Transcript 1 Protein, TLT-1, Triggering Receptor Expressed on Myeloid Cells-Like Protein 1, TREML1, TLT1

    分子量
    16.9 kDa
    UniProt
    Q86YW5
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