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TREML1 Protein (AA 16-162) (His tag)

TREML1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097703
发货至: 中国
  • 抗原 See all TREML1 蛋白
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    蛋白类型
    Recombinant
    产品特性
    AA 16-162
    宿主
    • 6
    • 4
    资源
    • 5
    • 3
    • 1
    • 1
    人细胞
    标记
    This TREML1 protein is labelled with His tag.
    原理
    Recombinant Human TREML1/TLT-1 (C-6His)
    序列
    QGIVGSLPEV LQAPVGSSIL VQCHYRLQDV KAQKVWCRFL PEGCQPLVSS AVDRRAPAGR RTFLTDLGGG LLQVEMVTLQ EEDAGEYGCM VDGARGPQIL HRVSLNILPP EEEEETHKIG SLAENAFSDP AGSANPLEPS QDEKSIPVDH HHHHH
    产品特性
    Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1/TREML1 produced by transfected human cells is a secreted protein with sequence (Gln16-Pro162) of Human TREML1 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TREML1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    别名
    tlt-1 (TREML1 产品)
    别名
    GLTL1825 Protein, PRO3438 Protein, TLT-1 Protein, TLT1 Protein, dJ238O23.3 Protein, 5430401J17Rik Protein, RGD1565175 Protein, triggering receptor expressed on myeloid cells 2 Protein, triggering receptor expressed on myeloid cells like 1 Protein, triggering receptor expressed on myeloid cells-like 1 Protein, LOC474898 Protein, TREML1 Protein, Treml1 Protein
    Sub Type
    Fusionprotein
    背景
    Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
    Alternative Names: Trem-Like Transcript 1 Protein, TLT-1, Triggering Receptor Expressed on Myeloid Cells-Like Protein 1, TREML1, TLT1
    分子量
    16.88 kDa
    UniProt
    Q86YW5
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